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MYP_082958
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Basic Information
TAM-riMitP
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
LIKKXLKALKKLNI
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093843 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
TAM
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Rhodamine conjugation
Aib, α-amino isobutyric acid
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22148546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0148642 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: U-373MG
67.15 μM
LD50
PMID22148546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0219056 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID22148546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0235414 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID22148546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0416840 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: U-373MG
100 μM
LD50
PMID22148546 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/