Peptide Database

Peptide NameIslet amyloid polypeptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC115H173N33O33

DescriptionStandard

        TQRLANFLIHSSNNFGAIFSPPN
    

Molecular Weight2545.80 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)0.49

Net Charge (pH 7.4) 0.24

Charge Density (pH 7.0) 0.0211

GRAVY Index-0.14

Hydrophobic Moment 0.48

Boman Index0.13

Instability Index30.74

Aliphatic Index 76.52

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1072.89

LogP -12.99

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 78.0

Heavy Atoms 181.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293388 VERIFIED: YES

Provenance & Taxonomy

OrganismLepus europaeus [Animal]

FamilyIslet amyloid polypeptide

Tax ID9983

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour