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MYP_082876
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Basic Information
C4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C54H105N15O10
Standard
Sequence
KRKILILIK
Physicochemical Analysis
1124.51 Da
11.26
3.76
3.55
0.4175
0.54
0.52
-0.09
69.04
216.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
436.08
0.16
16.0
14.0
43.0
79.0
0.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0048278 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0065202 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: U-937
64 μM
LD50
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0212431 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli DH5alpha
32 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0248439 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0324940 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus xylosus
8 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
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