Peptide Database

Peptide NameE3 ubiquitin/ISG15 ligase TRIM25

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral budding inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Standard StatusStandard

Sequence Length630 amino acids

Chemical FormulaC3138H4956N876O927S37

DescriptionStandard

        MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICSPK
    

Molecular Weight70972.64 Da

Isoelectric Point (pI)8.44

Net Charge (pH 7.0)10.31

Net Charge (pH 7.4) 8.31

Charge Density (pH 7.0) 0.0164

GRAVY Index-0.44

Hydrophobic Moment 0.74

Boman Index-0.06

Instability Index54.27

Aliphatic Index 76.49

Aromaticity 0.0746

Extinction Coeff. Reduced 63830.00

Extinction Coeff. Oxidized 65580.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321162 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTRIM

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Tyr278

Bio-Activity Profile

Function

Antiviral Release inhibition Budding inhibition