Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC347H536N82O88S10

DescriptionStandard

        MKPLLVVFVFLFLWDPVLAGINSLSSEMHKKCYKNGICRFECYKSEMLVAYCMFQLECCVKGNPAP
    

Molecular Weight7585.11 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)1.53

Net Charge (pH 7.4) 1.16

Charge Density (pH 7.0) 0.0232

GRAVY Index0.43

Hydrophobic Moment 0.54

Boman Index0.21

Instability Index50.89

Aliphatic Index 90.00

Aromaticity 0.1364

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2682.62

LogP -14.54

H-bond Donors 96.0

H-bond Acceptors 101.0

Rotatable Bonds 246.0

Heavy Atoms 527.0

Ring Count 15.0

Amide Bonds 69.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0016065 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence