Peptide Database

Peptide NameDPV3/10

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC97H181N49O23

DescriptionStandard

        RKKRRRESRRARRSPRHL
    

Molecular Weight2401.79 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)9.85

Net Charge (pH 7.4) 9.59

Charge Density (pH 7.0) 0.5471

GRAVY Index-2.92

Hydrophobic Moment 0.86

Boman Index-1.42

Instability Index231.58

Aliphatic Index 27.22

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1264.81

LogP -16.35

H-bond Donors 51.0

H-bond Acceptors 34.0

Rotatable Bonds 87.0

Heavy Atoms 169.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024543 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0112797 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0252521 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV/CAP37-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition for conjugation

C-TermNone

Other ModsN-term detail: Cys added to N -terminus for conjugation of report

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa; HCT116; HL-60; K562; Molt4; NIH-3T3; primary hepatocyte cultures

MethodCellular uptake assay

RECORD: Rec_0315981 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

RECORD: Rec_0335501 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCysteine addition

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery