Peptide Database

Peptide NameLWamide I

Function Ontology

Developmental biology ▸ Development regulation

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC35H52N10O7

DescriptionStandard

        RPPGLW
    

Molecular Weight724.85 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.1267

GRAVY Index-0.87

Hydrophobic Moment 0.40

Boman Index0.01

Instability Index112.00

Aliphatic Index 65.00

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 268.93

LogP -0.50

H-bond Donors 9.0

H-bond Acceptors 8.0

Rotatable Bonds 17.0

Heavy Atoms 52.0

Ring Count 4.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007542 VERIFIED: NO

Provenance & Taxonomy

OrganismHydractinia echinata [Animal]

FamilyLWamide

Tax ID35630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Growth regulation Development regulation

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0074033 VERIFIED: NO

Provenance & Taxonomy

OrganismHydractinia echinata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Development regulator

RECORD: Rec_0074038 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0173321 VERIFIED: NO

Provenance & Taxonomy

OrganismHydractinia echinata [Animal]

FamilyLWamide neuropeptide

Tax ID35630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

LWamide Neuropeptide