Peptide Database

Peptide NameCecropin-B type 2 (Cecropin-B2) [Cleaved into: Cecropin-B (AalCecB); Cecropin-B amidated isoform]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC296H503N75O75S

DescriptionStandard

        MNFSKLFALVLLIGLVLLTGQTEAGGLKKLGKKLEGVGKRVFKASEKALPVLTGYKAIGK
    

Molecular Weight6344.68 Da

Isoelectric Point (pI)10.24

Net Charge (pH 7.0)7.50

Net Charge (pH 7.4) 7.26

Charge Density (pH 7.0) 0.1250

GRAVY Index0.40

Hydrophobic Moment 0.72

Boman Index0.18

Instability Index9.59

Aliphatic Index 123.50

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2412.99

LogP -15.94

H-bond Donors 84.0

H-bond Acceptors 84.0

Rotatable Bonds 225.0

Heavy Atoms 447.0

Ring Count 5.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280525 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes albopictus [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria

RECORD: Rec_0351034 VERIFIED: NO