Peptide Database

Peptide NameIdursulfase

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length430 amino acids

Chemical FormulaC2186H3320N572O641S11

DescriptionStandard

        SETQANSTTDALNVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVPPRCPVPSFHVELCREGKNLLKHFRFRDLEEDPYLPG
    

Molecular Weight48221.91 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-13.41

Net Charge (pH 7.4) -14.47

Charge Density (pH 7.0) -0.0312

GRAVY Index-0.32

Hydrophobic Moment 0.81

Boman Index0.04

Instability Index42.10

Aliphatic Index 81.40

Aromaticity 0.1093

Extinction Coeff. Reduced 55810.00

Extinction Coeff. Oxidized 56185.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089521 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation

Bio-Activity Profile

Function

Enzyme replacement

Half-Life44 Ã‚Â± 19 minutes