Peptide Database

Peptide NamePenaeidin-3a (P3-a) (Pen-3a)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC388H614N114O99S9

DescriptionStandard

        MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYSG
    

Molecular Weight8748.31 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)9.50

Net Charge (pH 7.4) 9.11

Charge Density (pH 7.0) 0.1159

GRAVY Index0.18

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index42.26

Aliphatic Index 74.76

Aromaticity 0.0976

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3323.56

LogP -34.69

H-bond Donors 124.0

H-bond Acceptors 119.0

Rotatable Bonds 267.0

Heavy Atoms 610.0

Ring Count 19.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014791 VERIFIED: YES

Provenance & Taxonomy

OrganismPenaeus vannamei [Animal]

FamilyPenaeidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Non-hemolytic

TargetN. crassa

RECORD: Rec_0071805 VERIFIED: YES

Provenance & Taxonomy

OrganismPenaeus vannamei [Animal]

FamilyPenaeidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0150970 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0152454 VERIFIED: NO

Provenance & Taxonomy

OrganismLitopenaeus vannamei [Animal]

Tax ID6689

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0213516 VERIFIED: YES

Provenance & Taxonomy

OrganismPenaeus vannamei [Animal]

FamilyPenaeidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)