Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC433H698N120O134S8

DescriptionStandard

        MKTFWFAVAVAVVLTSICIQESPAVPGPEVQELEELEEPMSIESLVSDQEEPSEDSWKMPSSIREKRGIKCRFRCSHGVCGLSCKKRRG
    

Molecular Weight9985.42 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-2.43

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0273

GRAVY Index-0.31

Hydrophobic Moment 0.54

Boman Index-0.05

Instability Index91.68

Aliphatic Index 74.38

Aromaticity 0.0562

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4073.62

LogP -40.75

H-bond Donors 146.0

H-bond Acceptors 141.0

Rotatable Bonds 335.0

Heavy Atoms 695.0

Ring Count 14.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012773 VERIFIED: NO

Provenance & Taxonomy

OrganismNotothenia angustata [Animal]

FamilyHepcidin

Tax ID8210

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0369174 VERIFIED: NO