Peptide Database

Peptide NameSLAY-screened peptide P2092

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC82H140N26O25S

DescriptionStandard

        PPPSRSVGPILALCRSSAN
    

Molecular Weight1922.21 Da

Isoelectric Point (pI)10.39

Net Charge (pH 7.0)1.95

Net Charge (pH 7.4) 1.88

Charge Density (pH 7.0) 0.1026

GRAVY Index-0.01

Hydrophobic Moment 0.48

Boman Index0.03

Instability Index112.08

Aliphatic Index 87.37

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 794.57

LogP -11.17

H-bond Donors 29.0

H-bond Acceptors 28.0

Rotatable Bonds 56.0

Heavy Atoms 134.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401819 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/