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MYP_082517
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Basic Information
Cholecystokinin-58
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
58 amino acids
C285H459N89O84S3
Standard
Sequence
AVQKVDGESRAHLGALLARYIQQARKAPSGRVSMIKNLQSLDPSHRISDRDYMGWMDF
Physicochemical Analysis
6572.43 Da
9.81
2.97
2.67
0.0513
-0.56
0.67
-0.14
43.09
79.14
0.0690
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2828.14
-29.82
100.0
92.0
222.0
461.0
9.0
62.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001465 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Cholecystokinin
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
52:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation
CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0277018 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cholecystokinin
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
52:Sulfotyrosine
Bio-Activity Profile
Myotropic
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperIsolation and characterization of cholecystokinin-58 (CCK-58) from porcine brain PMID6468664 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6468664/
RECORD: Rec_0302465 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Gastrin/cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr52 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID6468664 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6468664/
RECORD: Rec_0355267 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Gastrin/cholecystokinin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr52 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID6468664 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6468664/