Peptide Database

Peptide NameEsculentin-1-OG2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC219H366N60O58S3

DescriptionStandard

        GLFSKFAGKGIKNFLIKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC
    

Molecular Weight4863.81 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)4.83

Net Charge (pH 7.4) 4.53

Charge Density (pH 7.0) 0.1049

GRAVY Index0.19

Hydrophobic Moment 0.71

Boman Index0.13

Instability Index-0.64

Aliphatic Index 97.39

Aromaticity 0.0652

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1904.31

LogP -15.54

H-bond Donors 68.0

H-bond Acceptors 67.0

Rotatable Bonds 174.0

Heavy Atoms 340.0

Ring Count 4.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412362 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana margaretae [Animal]

FamilyEsculentin

Structure & Mods

ConfigLinear peptide with a single intramolecular disulfide-stabilized loop [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Disulfide40-46

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity0.7 μM

MethodMIC

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