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MYP_082504
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Basic Information
R[G4a]-SHa
Anticancer
Antimicrobial
Antimicrobial ▸ Antifungal
Standard
13 amino acids
C68H110N14O15S
Standard
Sequence
FLKGLMGVIASLF
Physicochemical Analysis
1395.75 Da
8.75
0.76
0.55
0.0584
1.84
0.42
0.66
-3.83
150.00
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
458.77
-0.30
16.0
17.0
46.0
98.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0408312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is unique and shows only very low similarity (64.29%) to Lausporin-1 L:23%, G=F: 15%. Chemical modification: A10 is D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
cervical cancer Hela cells
60 μM
IC50
PaperSynthesis of Temporin-SHa Retro Analogs with Lysine Addition/Substitution and Antibiotic Conjugation to Enhance Antibacterial, Antifungal, and Anticancer Activities.
RECORD: Rec_0422498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is unique and shows only very low similarity (64.29%) to Lausporin-1 L:23%, G=F: 15%. Chemical modification: A10 is D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
S. typhi ATCC 14028
50 μM
MIC
PaperSynthesis of Temporin-SHa Retro Analogs with Lysine Addition/Substitution and Antibiotic Conjugation to Enhance Antibacterial, Antifungal, and Anticancer Activities.
RECORD: Rec_0423080 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
APD analysis reveals that this sequence is unique and shows only very low similarity (64.29%) to Lausporin-1 L:23%, G=F: 15%. Chemical modification: A10 is D-amino acid; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
human RBC: HC50 13.8 uM; hemolytic. Breast cancer cells MCF-7
53 μM
IC50
PaperSynthesis of Temporin-SHa Retro Analogs with Lysine Addition/Substitution and Antibiotic Conjugation to Enhance Antibacterial, Antifungal, and Anticancer Activities.
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