Peptide Database

Peptide Namebeta-Defensin, DEFB31

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC176H276N48O56S6

DescriptionStandard

        DECPSEYYECRLKCNADREAIRYCADFSICCKLKI
    

Molecular Weight4152.75 Da

Isoelectric Point (pI)5.10

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0369

GRAVY Index-0.46

Hydrophobic Moment 0.65

Boman Index-0.20

Instability Index31.69

Aliphatic Index 64.29

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1713.03

LogP -15.74

H-bond Donors 66.0

H-bond Acceptors 61.0

Rotatable Bonds 138.0

Heavy Atoms 286.0

Ring Count 5.0

Amide Bonds 35.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0114062 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-30; 10-24; 14-31

Bio-Activity Profile

Function

Antimicrobial