Peptide Database

Peptide NameL-amino-acid oxidase (EC 1.4.3.2) (Antiparasitic protein) (APP) (Serum L-amino-acid oxidase) (SR-LAAO)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length527 amino acids

Chemical FormulaC2617H4104N718O788S18

DescriptionStandard

        MDLHRAPWKSSAAAAVLLLALFSGAAASSVEKNLAACLRDNDYDQLLQTVQDGLPHINTSNHVVIVGAGVAGLTAAKLLQDAGHRVTIVEANSRIGGRVETYRNKEEGWYADLGAMRIPSDHSIFRWFAKTLGVKLNPFIMDDHNTFYFVNGLLKRTYTVEANPDILNYKVRSSEKGKSANTLFQDALQKVKDEVEAHGCRAALMKYDKYSAKEYLKEVAGLSSEALRMIGDLLNEQSLMYTALSEMIYDQADVNDNVQYDEVTGGTDLFPRAFLSVLDVPILLNSKVQRIRRSRDGVTVSFKESQRSSLTDLHADMVLVTTTAKAALYMDFEPSLSIRKMEALRAVHYDSSTKIILTFSSRFWEEDGIRGGKSITDRPSRYIYYPSHTFPANSSVGVLLASYTWSDDSLLLQAASDEELKEMALRDLVKIHGERVRALCTGVVVKKWSLDPYSFGAFALFTPYQHLEYAKELFRSEGRVHFAGEHTAFPHAWMESAMKSAIRAATNINKQTLLNEGMNECPAPDEL
    

Molecular Weight58810.09 Da

Isoelectric Point (pI)6.13

Net Charge (pH 7.0)-6.15

Net Charge (pH 7.4) -7.34

Charge Density (pH 7.0) -0.0117

GRAVY Index-0.23

Hydrophobic Moment 0.72

Boman Index0.01

Instability Index44.47

Aliphatic Index 87.97

Aromaticity 0.0911

Extinction Coeff. Reduced 69790.00

Extinction Coeff. Oxidized 70040.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107322 VERIFIED: YES

Provenance & Taxonomy

OrganismSiganus canaliculatus [other]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Non-hemolytic

TargetT. brucei

RECORD: Rec_0208745 VERIFIED: YES

Provenance & Taxonomy

OrganismSiganus canaliculatus [other]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0263197 VERIFIED: YES

Provenance & Taxonomy

OrganismSiganus canaliculatus [other]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Non-hemolytic

TargetC. irritans

RECORD: Rec_0351351 VERIFIED: YES

Provenance & Taxonomy

OrganismSiganus canaliculatus [other]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Non-hemolytic

TargetV. cholerae (Gram-negative)