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MYP_082476
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Basic Information
Cecropin-A (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Standard
34 amino acids
C154H269N45O40
Standard
Sequence
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL
Physicochemical Analysis
3391.06 Da
10.39
5.76
5.54
0.1694
0.02
0.73
0.05
16.77
103.53
0.0294
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1376.56
-11.96
47.0
46.0
121.0
239.0
2.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317154 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
100 microM ) , Bacillus cereus ( MIC = 100 microM ) , Bacillus subtilis ( MIC = 100 microM ) , Bacillus thuringiensis ( MIC = 100 microM ) , L. monocytogenes ( MIC = 100 microM ) , Staphylococcus aureus ( MIC =
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli D22
0.25-0.5 μM
MIC
PMID10400619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10400619/
RECORD: Rec_0325562 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Cecropin
7159
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Infection inhibition
Tacaribe virus | Vero cells
33.39 μM
EC90
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperAntiviral activity of antimicrobial cationic peptides against Junin virus and herpes simplex virus. | Albiol Matanic VC, Castilla V. | Int J Antimicrob Agents. 2004 Apr;23(4):382-9. | DOI:10.1016/j.ijantimicag.2003.07.022 | PMID:15081088 PMID15081088 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15081088/
RECORD: Rec_0325693 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Linear
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Micrococcus luteus
10-25 μg/mL
MIC
PMID10400619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10400619/
RECORD: Rec_0339110 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Linear
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fusarium oxysporum
2.5-5 μg/mL
MIC
PMID10400619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10400619/
RECORD: Rec_0340290 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Cecropin
7159
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Infection inhibition
Tacaribe virus | Vero cells
1.96 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperAntiviral activity of antimicrobial cationic peptides against Junin virus and herpes simplex virus. | Albiol Matanic VC, Castilla V. | Int J Antimicrob Agents. 2004 Apr;23(4):382-9. | DOI:10.1016/j.ijantimicag.2003.07.022 | PMID:15081088 PMID15081088 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15081088/
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