‹ ›
MYP_082471
← PREVIOUS NEXT → BACK
Basic Information
Brevinin-1AA1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
24 amino acids
C127H200N30O28S2
Standard
Sequence
FFPSIAGLAAKFLPKIFCSITKRC
Physicochemical Analysis
2659.26 Da
9.85
3.74
3.50
0.1557
0.86
0.62
0.28
43.70
93.75
0.1667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
915.69
-4.67
34.0
34.0
84.0
187.0
6.0
23.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0201794 VERIFIED: YES
Provenance & Taxonomy
Lithobates berlandieri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0217361 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50 μg/mL
MIC
RECORD: Rec_0220018 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus IS10#
5 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0239231 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
5 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0242628 VERIFIED: YES
Provenance & Taxonomy
Amolops afghanus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli IS117#
50 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
FIRST PREV 1 2 3 4 5 6 ... 8 NEXT LAST
Showing 5 records on this page · Page 4 of 8