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MYP_082466
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Basic Information
Cathelicidin, EA-CATH1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
25 amino acids
C141H235N43O31S
Standard
Sequence
KRRGSVTTRYQFLMIHLLRPKKLFA
Physicochemical Analysis
3060.71 Da
12.00
6.84
6.58
0.2737
-0.35
0.41
-0.20
49.68
93.60
0.1200
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1231.28
-8.31
46.0
40.0
104.0
216.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0235420 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Escherichia coli ATCC25922, Escherichia coli 090223 (IS), Serratia marcescens 091379 (IS), Klebsiella pneumoniae 091400 (IS), Salmonella typhi 091408 (IS), Cryptococcus neoformans (IS)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Candida glabrata 090902
100 μg/mL
MIC
PMID20423460 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20423460/
RECORD: Rec_0249776 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Escherichia coli ATCC25922, Escherichia coli 090223 (IS), Serratia marcescens 091379 (IS), Klebsiella pneumoniae 091400 (IS), Salmonella typhi 091408 (IS), Cryptococcus neoformans (IS)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Proteus mirabilis
100 μg/mL
MIC
PMID20423460 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20423460/
RECORD: Rec_0258271 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Escherichia coli ATCC25922, Escherichia coli 090223 (IS), Serratia marcescens 091379 (IS), Klebsiella pneumoniae 091400 (IS), Salmonella typhi 091408 (IS), Cryptococcus neoformans (IS)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella oxytoca
100 μg/mL
MIC
PMID20423460 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20423460/
RECORD: Rec_0261155 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0284876 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Escherichia coli ATCC25922, Escherichia coli 090223 (IS), Serratia marcescens 091379 (IS), Klebsiella pneumoniae 091400 (IS), Salmonella typhi 091408 (IS), Cryptococcus neoformans (IS)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Candida albicans ATCC 2002
9.4 μg/mL
MIC
PMID20423460 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20423460/
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