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MYP_082452
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Basic Information
GRFT
Antiviral
Standard
119 amino acids
C549H829N151O182S2
Standard
Sequence
SLTHRKFGGSGGSPFSGLSSIAVRSGSYLDAIIDGVHHGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
Physicochemical Analysis
12520.49 Da
5.39
-3.27
-3.66
-0.0275
-0.28
0.57
0.11
39.33
68.82
0.1176
11920.00
11920.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
5346.73
-70.39
189.0
184.0
408.0
884.0
20.0
127.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0141472 VERIFIED: YES
Provenance & Taxonomy
Griffithsia sp. [Plant]
Lectin
373036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
320 μg/mL
IC50
PaperBroad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae PMID20032190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20032190/
RECORD: Rec_0160821 VERIFIED: YES
Provenance & Taxonomy
Griffithsia sp. [Plant]
Lectin
373036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
0.0032 μg/mL
EC50
PaperBroad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae PMID20032190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20032190/
RECORD: Rec_0181436 VERIFIED: YES
Provenance & Taxonomy
Griffithsia sp. [Plant]
Lectin
373036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
10 μg/mL
IC50
PaperBroad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae PMID20032190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20032190/
RECORD: Rec_0390567 VERIFIED: YES
Provenance & Taxonomy
Griffithsia sp. [Plant]
Lectin
373036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
3100 μg/mL
IC50
PaperBroad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae PMID20032190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20032190/
RECORD: Rec_0409803 VERIFIED: YES
Provenance & Taxonomy
Griffithsia sp. [Plant]
Lectin
373036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
52 μg/mL
EC50
PaperBroad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae PMID20032190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20032190/
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