Peptide Database

Peptide NamePeptide 183

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC110H179N39O23

DescriptionStandard

        RPDKPRPYFPRKRPPRPVR
    

Molecular Weight2415.85 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.3557

GRAVY Index-2.31

Hydrophobic Moment 0.47

Boman Index-0.83

Instability Index73.28

Aliphatic Index 15.26

Aromaticity 0.1053

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1006.56

LogP -8.17

H-bond Donors 35.0

H-bond Acceptors 30.0

Rotatable Bonds 69.0

Heavy Atoms 172.0

Ring Count 9.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161571 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus DSM 6247

Activity128 μg/mL

MethodMIC

RECORD: Rec_0283351 VERIFIED: YES