Peptide Database

Peptide NameGaegurin-LK2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC351H582N90O104S7

DescriptionStandard

        MFTMKKSLLLIFFLGTINLSLCEEERNAEEEKRDGDDEMDVEVQKRFLGPIIKMATGILPTAICKGLKKC
    

Molecular Weight7951.37 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0216

GRAVY Index-0.08

Hydrophobic Moment 0.67

Boman Index0.01

Instability Index44.21

Aliphatic Index 96.14

Aromaticity 0.0571

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3145.75

LogP -23.98

H-bond Donors 110.0

H-bond Acceptors 110.0

Rotatable Bonds 281.0

Heavy Atoms 552.0

Ring Count 6.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380680 VERIFIED: YES

Provenance & Taxonomy

OrganismLimnonectes kuhlii [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

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