Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC596H938N168O161S4

DescriptionStandard

        MMARPYHVVVVLLLLESSARFGEGASNPGVVARITRKGLEYGKGTELKELPAIRLPDFSGSFKMGWFGRGSYNFHSLKIHHFEVRNSDLNLLPGLGIRASLSNNDLSMGGNWKVKKGFL
    

Molecular Weight13161.11 Da

Isoelectric Point (pI)10.06

Net Charge (pH 7.0)6.86

Net Charge (pH 7.4) 6.41

Charge Density (pH 7.0) 0.0576

GRAVY Index-0.13

Hydrophobic Moment 0.77

Boman Index0.06

Instability Index14.94

Aliphatic Index 90.08

Aromaticity 0.1008

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5263.84

LogP -47.68

H-bond Donors 185.0

H-bond Acceptors 176.0

Rotatable Bonds 439.0

Heavy Atoms 929.0

Ring Count 23.0

Amide Bonds 125.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0292499 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocitellus parryii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence