Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length106 amino acids

Chemical FormulaC531H869N133O151S11

DescriptionStandard

        MKLFLVLLILLFEVSEGTNLVHCCFLCTDTARSRKCFSTIAGYCKKKCMLGEIYDKPCTKGKLCCISESKKNTYQKAIQQPEPSSKPDLKLDYVILPTVTLGTIPQ
    

Molecular Weight11885.10 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.07

Charge Density (pH 7.0) 0.0519

GRAVY Index0.04

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index36.31

Aliphatic Index 93.77

Aromaticity 0.0755

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4555.66

LogP -38.98

H-bond Donors 165.0

H-bond Acceptors 169.0

Rotatable Bonds 400.0

Heavy Atoms 826.0

Ring Count 15.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345172 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence