Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC348H576N104O86S8

DescriptionStandard

        MKLLLLTLAALLLLSQLTPGGTQKCWNLRGRCRHRCSRKERVYVYCTNGKMCCVKPRYQPKEKPWPI
    

Molecular Weight7849.46 Da

Isoelectric Point (pI)10.07

Net Charge (pH 7.0)11.52

Net Charge (pH 7.4) 11.15

Charge Density (pH 7.0) 0.1720

GRAVY Index-0.37

Hydrophobic Moment 0.48

Boman Index-0.14

Instability Index21.76

Aliphatic Index 85.82

Aromaticity 0.0746

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3087.79

LogP -25.11

H-bond Donors 116.0

H-bond Acceptors 107.0

Rotatable Bonds 260.0

Heavy Atoms 546.0

Ring Count 13.0

Amide Bonds 71.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0382896 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence