Peptide Database

Peptide NameDefensin-like 3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC70H127N23O17S2

DescriptionStandard

        KVSCQAHCLLLKKR
    

Molecular Weight1627.03 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)3.82

Net Charge (pH 7.4) 3.54

Charge Density (pH 7.0) 0.2732

GRAVY Index-0.09

Hydrophobic Moment 0.26

Boman Index-0.21

Instability Index46.04

Aliphatic Index 111.43

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 673.58

LogP -5.75

H-bond Donors 26.0

H-bond Acceptors 24.0

Rotatable Bonds 58.0

Heavy Atoms 112.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333321 VERIFIED: YES

Provenance & Taxonomy

OrganismMusca domestica [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity300 μg/mL

MethodMIC