Peptide Database

Peptide NameAlpha-defensin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC439H709N133O141S7

DescriptionStandard

        MRTLAILAAILLVALQAQAESLQERADEATTQEQPGEDDQDLAVSFEENGLSTPRASGPQARFTCHCRIGRCSWFETRFRSCTLLGLAANLCCR
    

Molecular Weight10330.59 Da

Isoelectric Point (pI)5.02

Net Charge (pH 7.0)-3.44

Net Charge (pH 7.4) -3.81

Charge Density (pH 7.0) -0.0366

GRAVY Index-0.17

Hydrophobic Moment 0.52

Boman Index-0.04

Instability Index50.16

Aliphatic Index 82.23

Aromaticity 0.0532

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4443.22

LogP -52.17

H-bond Donors 161.0

H-bond Acceptors 146.0

Rotatable Bonds 343.0

Heavy Atoms 720.0

Ring Count 10.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012565 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal