Peptide Database

Peptide Namealpha-Conotoxin RgIA

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC59H99N25O18S4

DescriptionStandard

        GCCSDPRCRYRCR
    

Molecular Weight1574.83 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.46

Charge Density (pH 7.0) 0.2093

GRAVY Index-1.20

Hydrophobic Moment 0.19

Boman Index-0.71

Instability Index-15.38

Aliphatic Index 0.00

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 729.09

LogP -10.46

H-bond Donors 32.0

H-bond Acceptors 25.0

Rotatable Bonds 49.0

Heavy Atoms 106.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062818 VERIFIED: NO

Provenance & Taxonomy

OrganismConus regius [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-8; 3-12

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0336533 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic