Peptide Database

Peptide NameL-amino-acid oxidase (BatroxLAAO) (LAO) (EC 1.4.3.2)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length506 amino acids

Chemical FormulaC2571H3985N691O770S16

DescriptionStandard

        MNVFFTFSLLFLAALGSCADDRNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRASEIKK
    

Molecular Weight57407.35 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-5.53

Net Charge (pH 7.4) -6.58

Charge Density (pH 7.0) -0.0109

GRAVY Index-0.41

Hydrophobic Moment 0.97

Boman Index-0.03

Instability Index40.71

Aliphatic Index 80.38

Aromaticity 0.1087

Extinction Coeff. Reduced 67730.00

Extinction Coeff. Oxidized 68105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161723 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops atrox [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Cytolytic Toxin Anticancer Cytotoxic Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria