Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC338H520N102O109S4

DescriptionStandard

        WCLESSQCQDLTTERHLLECLRACKPDLSAETPVFPGGADEQTPTESPRKYVTGHFRWGRFGRGNSSGASQ
    

Molecular Weight7884.62 Da

Isoelectric Point (pI)6.09

Net Charge (pH 7.0)-1.09

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.0153

GRAVY Index-0.80

Hydrophobic Moment 0.64

Boman Index-0.14

Instability Index65.03

Aliphatic Index 46.76

Aromaticity 0.0845

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3403.12

LogP -42.65

H-bond Donors 123.0

H-bond Acceptors 114.0

Rotatable Bonds 253.0

Heavy Atoms 553.0

Ring Count 15.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220912 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0229907 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyPOMC

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhe61 Amidation

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0270278 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyNPP

Tax ID10141

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide2-24

Other Mods61:Phenylalanine amide; 45:O-linked (GalNAc...) threonine; 65:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min