Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitor 1

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC30H43N5O7

DescriptionStandard

        LYPPP
    

Molecular Weight585.69 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0482

GRAVY Index-0.46

Hydrophobic Moment 0.21

Boman Index0.34

Instability Index109.72

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 173.58

LogP 0.85

H-bond Donors 4.0

H-bond Acceptors 7.0

Rotatable Bonds 10.0

Heavy Atoms 42.0

Ring Count 4.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346874 VERIFIED: YES

Provenance & Taxonomy

OrganismChanna striata [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity1.31 ± 0.02 μM

MethodIC50