Peptide Database

Peptide NameAlpha-defensin 15 (Defensin-related cryptdin-15)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC446H729N131O145S8

DescriptionStandard

        MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHINGTCRKGHLLYMLCCR
    

Molecular Weight10502.87 Da

Isoelectric Point (pI)5.32

Net Charge (pH 7.0)-3.36

Net Charge (pH 7.4) -3.79

Charge Density (pH 7.0) -0.0361

GRAVY Index-0.48

Hydrophobic Moment 0.62

Boman Index-0.13

Instability Index56.36

Aliphatic Index 81.72

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4502.12

LogP -49.31

H-bond Donors 161.0

H-bond Acceptors 152.0

Rotatable Bonds 360.0

Heavy Atoms 730.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0276545 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found