Peptide Database

Peptide NameTritrpticin [P9A][R2,3,12,13K]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC94H130N20O14

DescriptionStandard

        VKKFPWWWAFLKK
    

Molecular Weight1764.16 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.73

Net Charge (pH 7.4) 3.51

Charge Density (pH 7.0) 0.2869

GRAVY Index-0.35

Hydrophobic Moment 0.33

Boman Index0.13

Instability Index1.52

Aliphatic Index 60.00

Aromaticity 0.3846

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 555.18

LogP 3.62

H-bond Donors 20.0

H-bond Acceptors 18.0

Rotatable Bonds 53.0

Heavy Atoms 128.0

Ring Count 9.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394657 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetJurkat T-cell leukemia

Activity15.1 μM

MethodIC50

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