Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length205 amino acids

Chemical FormulaC1030H1561N227O314S10

DescriptionStandard

        SFSFFGNILYLALSTTLTVVMPIDDLAEVDYSLSSLPAVFQPFIDLDLKGTVFPAGNYTASPYVAAPFSVTDQSDSMLFLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight22468.39 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.53

Net Charge (pH 7.4) -15.82

Charge Density (pH 7.0) -0.0758

GRAVY Index0.46

Hydrophobic Moment 0.55

Boman Index0.29

Instability Index47.89

Aliphatic Index 94.20

Aromaticity 0.1366

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057443 VERIFIED: NO

Provenance & Taxonomy

OrganismTyrannus savana (Fork-tailed flycatcher) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria