Peptide Database

Peptide NameOdorranain-H1 antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune modulation ▸ Mast cell modulation

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC93H162N24O23S2

DescriptionStandard

        GIFGKILGVGKKVLCGLSGVC
    

Molecular Weight2048.56 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.1303

GRAVY Index1.23

Hydrophobic Moment 0.52

Boman Index0.44

Instability Index-5.56

Aliphatic Index 134.29

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 743.61

LogP -5.44

H-bond Donors 28.0

H-bond Acceptors 28.0

Rotatable Bonds 71.0

Heavy Atoms 142.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0259771 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyOdorranain

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide15-21

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans

Activity11.8 μg/mL

MethodMIC

RECORD: Rec_0264809 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyNigrocin

Tax ID167935

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity5.90 μg/mL

MethodMIC

RECORD: Rec_0305988 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyOdorranain

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide15-21

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

RECORD: Rec_0362302 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyOdorranain

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide15-21

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetBacillus subtilis

Activity5.9 μg/mL

MethodMIC

RECORD: Rec_0394698 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyOdorranain

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide15-21

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

Targetrabbit red blood cells

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