Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length235 amino acids

Chemical FormulaC1186H1828N276O356S9

DescriptionStandard

        TRTVPMLIDDLAEVDYSLNTLPAVFRQFIDLDLKGIVHPAGNYTGSTCVTTPFTIPDQSDSMLHLAFSEYFFQTSSFAYYTAGAFNVTITEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVVSLEQDSFTVEIQGSMEVFAVLPDSTTQLLFTMNVAANTSIALNIFDQKLVGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSVNAKLSKGFPLP
    

Molecular Weight25937.42 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-14.34

Net Charge (pH 7.4) -14.77

Charge Density (pH 7.0) -0.0610

GRAVY Index0.36

Hydrophobic Moment 0.62

Boman Index0.24

Instability Index37.58

Aliphatic Index 101.19

Aromaticity 0.1149

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389499 VERIFIED: NO

Provenance & Taxonomy

OrganismThinocorus orbignyianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria