Peptide Database

Peptide NameBrevinin-1CHc

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC100H160N22O23S2

DescriptionStandard

        FFPTIAGLTKLFCAITKKC
    

Molecular Weight2102.60 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.1441

GRAVY Index0.94

Hydrophobic Moment 0.56

Boman Index0.33

Instability Index15.14

Aliphatic Index 92.63

Aromaticity 0.1579

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 717.08

LogP -3.40

H-bond Donors 27.0

H-bond Acceptors 28.0

Rotatable Bonds 67.0

Heavy Atoms 147.0

Ring Count 4.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104725 VERIFIED: YES

Provenance & Taxonomy

OrganismRana chiricahuensis [Animal]

FamilyBrevinin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide13-19

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEscherichia coli

Activity80 μM

MethodMIC

RECORD: Rec_0117074 VERIFIED: YES

Provenance & Taxonomy

OrganismChiricahua leopard [Animal]

FamilyBrevinin

Tax ID33208

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide13-19

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0128869 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates chiricahuensis [Animal]

FamilyBrevinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

RECORD: Rec_0143011 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates chiricahuensis [Animal]

FamilyBrevinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

RECORD: Rec_0164614 VERIFIED: YES

Provenance & Taxonomy

OrganismRana chiricahuensis [Animal]

FamilyBrevinin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide13-19

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans

Activity20 μM

MethodMIC

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