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MYP_082034
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Basic Information
Glycomacropeptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Wound healing/Regeneration ▸ Wound healing
Standard
64 amino acids
C288H476N72O108S
Standard
Sequence
MAIPPKKNQDKTEIPTINTIASGEPTSTPTTEAVESTVATLEDSPEVIESPPEINTVQVTSTAV
Physicochemical Analysis
6707.34 Da
4.05
-7.48
-7.71
-0.1168
-0.37
0.41
0.05
64.17
77.66
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2856.95
-37.33
93.0
102.0
212.0
469.0
8.0
68.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010046 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glycomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Glycosylation-associated glycomacropeptide context
Bio-Activity Profile
Immunomodulatory Anti-inflammatory
Caco-2/15 cells
Superoxide scavenging assay
PaperGlycomacropeptide Prevents Iron/Ascorbate-Induced Oxidative Stress, Inflammation and Insulin Sensitivity with an Impact on Lipoprotein Production in Intestinal Caco-2/15 Cells | Foisy-Sauve, M. et al. | DOI: 10.3390/nu12041175 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0027767 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glycomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Wound healing Anti-inflammatory Barrier-protective
Rats
PaperProtective Effect of Glycomacropeptide on the Atopic Dermatitis-Like Dysfunctional Skin Barrier in Rats | Jimenez M. et al. | DOI: 10.1089/jmf.2019.0247 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0079730 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20030195150A1/en PatentUS 2003/0195150 A1
RECORD: Rec_0107932 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glycomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-inflammatory Mucin secretagogue Enteroprotective Nitric oxide-modulating
Rats
PaperGlycomacropeptide Ameliorates Indomethacin-Induced Enteropathy in Rats by Modifying Intestinal Inflammation and Oxidative Stress | Cervantes-Garcia, D. et al. | DOI: 10.3390/molecules25102351 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0143022 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Caseinomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Pancreatic secretagogue
Rats
PaperCaseinomacropeptide specifically stimulates exocrine pancreatic secretion in the anesthetized rat | Pedersen, NL. et al. | DOI: 10.1016/s0196-9781(00)00307-7 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
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