Peptide Database

Peptide NamePxt-7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC64H118N18O18

DescriptionStandard

        GGLIGTLTAKQIKK
    

Molecular Weight1427.73 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1969

GRAVY Index0.04

Hydrophobic Moment 0.47

Boman Index0.11

Instability Index22.86

Aliphatic Index 118.57

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 603.23

LogP -5.79

H-bond Donors 21.0

H-bond Acceptors 21.0

Rotatable Bonds 52.0

Heavy Atoms 100.0

Ring Count 0.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017459 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus tropicalis [Animal]

Tax ID8364

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsThe 'G' at position 1 is pyroglutamic acid

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus JCM 2151(Not active up to 150 μg/ml)

RECORD: Rec_0094048 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus tropicalis [Animal]

Tax ID8364

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsThe 'G' at position 1 is pyroglutamic acid

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic

TargetRat erythrocytes

RECORD: Rec_0121328 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus tropicalis [Animal]

Tax ID8364

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsThe 'G' at position 1 is pyroglutamic acid

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetGram-negative bacteria: Escherichia coli DH5α(Not active up to 150 μg/ml)

RECORD: Rec_0253990 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus tropicalis [Animal]

Tax ID8364

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsThe 'G' at position 1 is pyroglutamic acid

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic