Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC376H581N105O100S9

DescriptionStandard

        RKMFYFVFILFFIVAQLQSGCQAGLDYAPSFPAGEQGACKTCRLGRGKCRRMCLENEKVEGNYGLSFFCCRERI
    

Molecular Weight8460.86 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.37

Charge Density (pH 7.0) 0.0635

GRAVY Index-0.01

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index54.05

Aliphatic Index 65.95

Aromaticity 0.1486

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3331.37

LogP -29.54

H-bond Donors 124.0

H-bond Acceptors 114.0

Rotatable Bonds 282.0

Heavy Atoms 590.0

Ring Count 13.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329742 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence