Peptide Database

Peptide NamePelophylaxin-HB3

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC349H579N89O107S4

DescriptionStandard

        MFTSKKSLLLVFFLGAIPLSFCEEERGADEENGGEITEEEIKRGILTDTLKGAAKKVAGVLLDKLKCKITGGC
    

Molecular Weight7862.12 Da

Isoelectric Point (pI)5.41

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0207

GRAVY Index0.03

Hydrophobic Moment 0.53

Boman Index0.07

Instability Index26.44

Aliphatic Index 98.90

Aromaticity 0.0548

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3160.24

LogP -27.58

H-bond Donors 112.0

H-bond Acceptors 110.0

Rotatable Bonds 278.0

Heavy Atoms 549.0

Ring Count 5.0

Amide Bonds 73.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0199854 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax hubeiensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence