Peptide Database

Peptide NameSibaDef

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC202H324N64O60S6

DescriptionStandard

        ATCDLLSISTPWGSVNHAACAAHCLALNRGFRGGYCSSKAVCTCRK
    

Molecular Weight4801.52 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)3.91

Net Charge (pH 7.4) 3.53

Charge Density (pH 7.0) 0.0850

GRAVY Index0.19

Hydrophobic Moment 0.62

Boman Index0.07

Instability Index31.40

Aliphatic Index 70.22

Aromaticity 0.0652

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1980.47

LogP -26.27

H-bond Donors 78.0

H-bond Acceptors 72.0

Rotatable Bonds 152.0

Heavy Atoms 332.0

Ring Count 7.0

Amide Bonds 47.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0385206 VERIFIED: YES

Provenance & Taxonomy

OrganismSimulium bannaense [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus aureus ATCC 6538

Activity0.83 μM

MethodMIC

RECORD: Rec_0426210 VERIFIED: YES

Provenance & Taxonomy

OrganismSimulium bannaense [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (- at NA

MethodHemolysis

FIRST PREV 1 2 3

Showing 2 records on this page Ã‚Â· Page 3 of 3