Peptide Database

Peptide NameDefensin-B4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC461H755N131O148S8

DescriptionStandard

        MRASLLLFILLVYLAHAPQAQGVFGPRRCKGKLGYCRSKCQSKQVELGKCSTKAICCGISTGTSSSQGSHEVPVINSEPALESKPEPQDTQEEEATMVSE
    

Molecular Weight10757.24 Da

Isoelectric Point (pI)7.59

Net Charge (pH 7.0)0.64

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0064

GRAVY Index-0.29

Hydrophobic Moment 0.49

Boman Index-0.02

Instability Index53.36

Aliphatic Index 75.10

Aromaticity 0.0400

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4480.67

LogP -53.69

H-bond Donors 159.0

H-bond Acceptors 159.0

Rotatable Bonds 362.0

Heavy Atoms 748.0

Ring Count 12.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242691 VERIFIED: NO

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence