Peptide Database

Peptide NameCycloviolacin O11

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC128H200N38O38S8

DescriptionStandard

        PCGESCVWMYCISAAMGCSCRNKVCYRN
    

Molecular Weight3135.71 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.75

Charge Density (pH 7.0) 0.0678

GRAVY Index0.13

Hydrophobic Moment 0.32

Boman Index0.03

Instability Index56.84

Aliphatic Index 41.79

Aromaticity 0.1071

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1225.27

LogP -14.47

H-bond Donors 51.0

H-bond Acceptors 48.0

Rotatable Bonds 99.0

Heavy Atoms 212.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059235 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)