Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC432H682N122O124S14

DescriptionStandard

        MKVFSIAVAVTLVLAFICILESSAVPFTGVQELEEAGSNDTPVAAHQEMSMESWMMPNHIRQKRQSHLSLCRWCCNCCKGNKGCGFCCRF
    

Molecular Weight10017.69 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.18

Hydrophobic Moment 0.57

Boman Index0.10

Instability Index62.92

Aliphatic Index 73.67

Aromaticity 0.0778

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3924.50

LogP -40.02

H-bond Donors 144.0

H-bond Acceptors 142.0

Rotatable Bonds 330.0

Heavy Atoms 692.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136561 VERIFIED: NO

Provenance & Taxonomy

OrganismMicropterus dolomieu [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0318895 VERIFIED: YES