Peptide Database

Peptide NameInterleukin-1 beta

Function Ontology

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC804H1263N221O238S7

DescriptionStandard

        APAFRYTRSQSFDIFDINQKCFVLESPTQLVALHLQGPSSSQKVRLNIALYRPRGPRGSAGTGQMPVALGIKGYKLYMSCVMSGTEPTLQLEEADVMRDIDSVELTRFIFYRLDSPTEGTTRFESAAFPGWFICTSLQPRQPVGITNQPDQVNIATYKLSGR
    

Molecular Weight18057.42 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0177

GRAVY Index-0.25

Hydrophobic Moment 0.53

Boman Index0.01

Instability Index62.54

Aliphatic Index 77.65

Aromaticity 0.0988

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7376.22

LogP -77.30

H-bond Donors 258.0

H-bond Acceptors 249.0

Rotatable Bonds 585.0

Heavy Atoms 1270.0

Ring Count 30.0

Amide Bonds 176.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0230368 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyIL-1 family

Tax ID9031; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor IL-1 family Chemokine-like Growth factor signaling Angiogenic