Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC581H889N165O172S3

DescriptionStandard

        MRGSKGNIGLVPKEVADNLRGREFNSFDDFRNAFWKEYSTSSYASEFSKSNIKRMGQGLAPKAPASQQYKSISSYVLHHKNPIYNGGGVYDLDNLIISSPRMHQEILDKGFHFNK
    

Molecular Weight13033.47 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.40

Charge Density (pH 7.0) 0.0422

GRAVY Index-0.73

Hydrophobic Moment 0.60

Boman Index-0.09

Instability Index53.52

Aliphatic Index 62.78

Aromaticity 0.1217

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5494.18

LogP -59.61

H-bond Donors 189.0

H-bond Acceptors 184.0

Rotatable Bonds 437.0

Heavy Atoms 921.0

Ring Count 24.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139517 VERIFIED: NO

Provenance & Taxonomy

OrganismClostridium butyricum [Bacterium]

FamilyPyocin/Colicin

Tax ID1492

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal