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MYP_081815
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Basic Information
Uperin-2.4 (toads, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C87H148N24O24
Standard
Sequence
GILDFAKTVVGGIRNALGI
Physicochemical Analysis
1914.25 Da
8.75
0.76
0.56
0.0400
0.96
0.64
0.37
10.76
143.68
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
775.66
-6.40
27.0
25.0
64.0
135.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0169389 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ636
RECORD: Rec_0175156 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
P.haemolytica
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ636
RECORD: Rec_0193436 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
L.innocua
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ636
RECORD: Rec_0203290 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0211763 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Pasteurella haemolytica
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01142
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