Peptide Database

Peptide NameChimeric CNP-J

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC180H311N57O51S3

DescriptionStandard

        GLSKGCFGLKLDRIGSMSGLGCVQQRKDSKKPPAKLQPR
    

Molecular Weight4185.94 Da

Isoelectric Point (pI)10.31

Net Charge (pH 7.0)6.74

Net Charge (pH 7.4) 6.49

Charge Density (pH 7.0) 0.1727

GRAVY Index-0.66

Hydrophobic Moment 0.45

Boman Index-0.20

Instability Index37.62

Aliphatic Index 70.00

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1769.36

LogP -20.79

H-bond Donors 63.0

H-bond Acceptors 61.0

Rotatable Bonds 147.0

Heavy Atoms 291.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265998 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide6-22

Bio-Activity Profile

Function

Natriuretic

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Intravenous), in vivo; 1874.4 s